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MEETING DETAILS
The First SKLRB Symposia on Frontiers in Periimplantation Biology
Organizers: Drs. Enkui Duan, Haibin Wang, Sudhansu K. Dey and Bruce D. Murphy
May 8-12, 2010
Beijing Friendship Hotel, Beijing, China
Abstract Deadline: January 31, 2010
Early Registration Deadline: January 31, 2010
Summary of Meeting
Embryo implantation involves an intricate communication between the embryo and uterus, failure at any critical stages leads to early pregnancy loss. It is also a major limiting factor in assisted reproduction. Periimplantation events include early embryo development, the crosstalk between the embryo and uterus and the development of the deciduum and placenta. A better understanding of the molecular mechanisms concerning periimplantation biology will not only improve our general cognition of life sciences, but also help in developing clinical strategies to combat reproductive disorders. With the economic development in China, the Chinese government has been paying more and more attention to the research concerning human health. SKLRB is the only national center for basic research in reproductive biology in China. By serving as the Chinese Center for WHO/Rockefeller Foundation Initiative on Implantation from 1999 to 2004, SKLRB has been a pioneer in China in promoting basic research, national and international collaborations, as well as pre- and post-doctoral training in the field of reproductive biology, with an aim to improving nationally and globally human health. This symposia entitled “SKLRB Symposia on Frontiers in Periimplantation Biology” sponsored by SKLRB is aimed at bringing in distinguished scientists in the field to exchange and discuss cutting edge basic and translational investigations pertaining to periimplantation biology in various model systems. The meeting is intended to provide a forum for extensive exchange and sharing of new information and development in the area, and to develop better communication among scientists across the world.
Scientific Advisory Committee
Anming Meng, Academician, Director of Institute of Zoology, CAS
Yixun Liu, Academician, SKLRB, Institute of Zoology, CAS
Cheng Zhu, Professor, SKLRB, Institute of Zoology, CAS
Qingyuan Sun, Professor, Director of SKLRB, Institute of Zoology, CAS
Organizing Committee
Cochairs:
Enkui Duan, Professor, Deputy Director of Institute of Zoology, CAS
Haibin Wang, Professor, SKLRB, Institute of Zoology, CAS
Sudhansu K. Dey, Professor, Cincinnati Children’s Hospital Medical Center, USA
Bruce D. Murphy, Professor, University of Montreal, Canada
Secretary-general:
Yan-ling Wang, Professor, SKLRB, Institute of Zoology, CAS
Hongmei Wang, Professor, SKLRB, Institute of Zoology, CAS
Scientific Program and Schedule
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| SATURDAY, MAY 8 |
| 02:00 - 06:00 PM Registration |
| 04:00 - 05:00 PM Opening Ceremony |
| 05:00 - 06:10 PM Keynote Address |
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Enkui Duan, SKLRB, Institute of Zoology, CAS
Introduction of Keynote Speaker
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Janet Rossant, Hospital for Sick Children, Canada
Making the Placenta- the Role of Trophoblast Stem Cells
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| 06:30 - 08:00 PM Dinner |
| SUNDAY, MAY 9 |
| 07:00 - 08:20 AM Breakfast |
| 07:40 - 08:20 AM Poster Setup |
| 08:20 - 12:00 AM Preimplantation Biology (S1) |
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Session Chairs: Magdalena Zernicka-Goetz, University of Cambridge, UK
Qingyuan Sun, SKLRB, Institute of Zoology, CAS
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Yumiko Saga, National Institute of Genetics, Japan
Functions of NANOS2 in the Maintenance of Embryonic Germ Cells and Spermatogonial Stem Cells in Mice
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Shaorong Gao, National Institute of Biological Sciences, China
Reprogramming of Differentiated Somatic Cells into Pluripotent Stem Cells
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Andras Nagy, Mount Sinai Hospital, Canada
Transposon-mediated Reprogramming Provides a Powerful Tool for Understanding Stem Cell Induction
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Qi Zhou, SKLRB, Institute of Zoology, China
Reprogramming and Stem Cell Research Progresses
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Guoliang Xia, China Agricultural University, China
Potential Mechanisms Governing Primordial Follicle Formation in Mice
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| 10:20 - 10:40 AM Coffee Break |
| 12:00 - 01:00 PM Lunch |
| 02:20 - 06:00 PM Preimplantation Biology (S2) |
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Session Chairs: Andras Nagy, Mount Sinai Hospital, Canada
Qi Zhou, SKLRB, Institute of Zoology, CAS
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Qingyuan Sun, SKLRB, Institute of Zoology, China
Molecular insights into mechanisms regulating faithful chromosome separation during mouse oocyte meiosis
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Magdalena Zernicka-Goetz, University of Cambridge, UK
Setting Aside Pluripotent Cells from the First Two Extra-embryonic Lineages in the Mouse Embryo
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Toshihiko Fujimori, National Institute for Basic Biology, Japan
Behaviors of Cell and Gene Expression during the Preimplantation Mouse Embryo
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Lei Li, SKLRB, Institute of Zoology, China
Maternal Control of Mouse Early Embryo Development
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Hiroshi Sasaki, Riken CDB, Japan
Cell Fate Regulation by Hippo Signaling in Preimplantation Embryos
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| 04:20 - 04:40 PM Coffee Break |
| 06:30 - 07:30 PM Dinner |
| 07:30 - 09:30 Poster Session (I: B1-B20) |
| Monday, MAY 10 |
| 07:00 - 08:20 AM Breakfast |
| 08:20 - 12:00 AM Uterine Development and Implantation Biology (S1) |
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Session Chairs: Carlos Simon, University of Valencia, Spain
Haibin Wang, SKLRB, Institute of Zoology, CAS
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Hyunjung (Jade) Lim, Konkuk University, Korea
Molecular and Cellular Aspects of the Embryonic Diapause in Mice: Involvement of Autophagy
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Bruce Murphy, University of Montreal, Canada
Uterine Signals in Embryonic Diapause
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Weinian Shou, Indiana University, USA
Co-chaperone FKBP52 in Regulating Transcriptional Activity of Progesterone Receptor and Implantation
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Zeng-ming Yang, Xiamen University, China
Global Analysis of Uterine mRNAs and microRNAs during Embryo Implantation
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Francesco DeMayo, Baylor College of Medicine, USA
Molecular Regulators of Postnatal Uterine Development and Function
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| 10:20 - 10:40 AM Coffee Break |
| 12:00 - 01:00 PM Lunch |
| 02:20 - 05:20 PM Uterine Development and Implantation Biology (S2) |
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Session Chairs: Bruce Murphy, University of Montreal, Canada
Zeng-ming Yang, Xiamen University, China
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Sanjoy Das, Cincinnati Children’s Hospital Medical Center, USA
Cell Cycle Signaling in Decidualization
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Hefeng Huang, Zhejiang University, China
Calcium-activated Potassium Channels are expressed in the human endometrium and mediate embryo implantation.
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Carlos Simon, University of Valencia, Spain
Human Endometrial CD98 Is Essential for Blastocyst Adhesion
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Thomas E. Spencer, Texas A & M University, USA
Comparative Aspects of Conceptus-Endometrial Interactions and Implantation
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| 03:40 - 04:00 PM Coffee Break |
| 05:30 - 07:00 PM Dinner |
| 07:00 - 09:30 PM Poster Session (II: B21-B40) |
| 07:00 - 09:00 PM Workshop |
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Session Chairs: Thomas E. Spencer, Texas A & M University, USA
Guoliang Xia, China Agricultural University, China
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Eo Jinwon, Konkuk University, Seoul, South Korea
Etv5 disruption causes subfertility due to ovarian defects in the immature and adult female mice
(Abstract No. B8)
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Mitsutoshi Yamada, Keio University, Japan
Identification of a novel gene encoding a high mobility group box protein and its specific expression and
essential role during preimplantation development (Abstract No. B10)
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William Shu-Biu Yeung, The University of Hong Kong, Hong Kong PRC
MicroRNA-34c is important for the first cell division in mouse embryos (Abstract No. B12)
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Qi Chen, SKLRB, Institute of Zoology, CAS
Transient β2-Adrenoceptor activation disrupts normal embryo spacing and compromised pregnancy in
mice (Abstract No. B22)
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Zhi Zhou, SKLRB, Institute of Zoology, CAS
Proprotein convertase furin is required for syncytiolization of trophoblast (Abstract No. B32)
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Wen-long Gao, SKLRB, Institute of Zoology, CAS
Detection of global DNA methylation and paternally imprinted H19 gene methylation in preeclampsia
(Abstract No. B36)
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| Tuesday, MAY 11 |
| 07:00 - 08:20 AM Breakfast |
| 08:20 - 12:00 AM Placental Biology and Reproductive Diseases (S1) |
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Session Chairs: Susan J Fisher, University of California, San Francisco, USA
Yan-ling Wang, SKLRB, Institute of Zoology, CAS
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Satoshi Tanaka, The University of Tokyo, Japan
Normalcy of trophoblast stem cells derived from cloned mouse embryos
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David R Armant, Wayne State University, USA
The EGF Signaling System in Trophoblast Development and Obstetric Pathology
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Hongmei Wang, SKLRB, Institute of Zoology, CAS
Ubiquitin Ligase Cullin 7 Induces Epithelial-Mesenchymal Transition in Human Choriocarcinoma Cells
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Stephen Lye, Toronto University, Canada
Mechanisms Underlying Decidual-Trophoblast Remodelling of the Uterine Vasculature
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Jay C Cross, University of Calgary, Canada
Signals that Drive Alternative Pathways of Trophoblast Differentiation
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| 10:20 - 10:40 AM Coffee Break |
| 12:00 - 01:00 PM Lunch and Nap |
| 02:20 - 05:20 PM Placental Biology and Reproductive Diseases (S2) |
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Session Chairs: Jay C Cross, University of Calgary, Canada
Hongmei Wang, SKLRB, Institute of Zoology, CAS
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Chun Peng, York University, Canada
Regulation of Placental Functions by microRNAs
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S. Ananth Karumanchi, Harvard Medical University, USA
Pathogenesis of Preeclampsia
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Yan-ling Wang, SKLRB, Institute of Zoology, CAS
Identification of the early biomarkers in the plasma of preeclamptic patients
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Susan J Fisher, University of California, San Francisco, USA
Derivation and Characterization of Self-Renewing Human Trophoblast Progenitors Reveals Their
Unique Properties
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| 03:40 - 04:00 PM Coffee Break |
| 05:20 – 05:30 PM Closing Remarks by Bruce Murphy |
| 06:00 – 09:00 PM Dinner and Entertainment |
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