Jing-Pian Peng

Introduction

Research Projects

Publications
Reproductive Immunology

 
  Brief Introduction  
 
 

 

Jing-Pian Peng

 

Ph.D., Professor

Subject Physiology
Tel(Fax)
 +86-010-64807183
Address State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences
1 Beichen West Road, Chaoyang District, Beijing 100101, P.R.China
E-mail pengjp@ioz.ac.cn
   
  On-going Research Projects  
 

 

1. PI, the State 863 High Technology R&D Project of China (Grant N0.: 2004AA215182) ): The molecular mechanism of CG anti-tumor DNA vaccine.

2. PI, the National Natural Science Foundation of China (Grant N0.: 30470204): The mechanism of immune contraception of ZPC. From Jan. 2005 to Dec. 2007

3. PI, the National Natural Science Foundation of China (Grant N0.: 30770246): The molecular mechanisms and function of CYP26A1 in embryo implantation in rat.

4. PI, the National Basic Research Program of China (973) (No.2006CB504006): The molecular mechanisms of trophoblast cell invasion and tumor cell invasion.

5. PI, the National Basic Research Program of China (2006CB944007): The molecular mechanisms of immune tolerance and immune rejection at maternal-fetal interface

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  Majors Publications  
 

 

1. Zhe Liu, Yun Chen, Ying Yang, Jing-pian Peng,* (2002) The effect on MHC class II expression and apoptosis in placenta by IFN- g administration. Contraception. 65: 177-184.

2. Chen Yun, Zhe Liu , Ying Yang, You-Zhen Chen and Jing- pian Peng,* ( 2002) Infertility in mice induced by the rhesus monkey chorionic gonadotropin b -subunit glycoprotein (rmCG b ) using DNA immunization. Mol. Cell Biochem. 231: 89-96.

3. Zhe Liu, Quan-Hong Sun, Ying Yang, Jia-Mei Liu, Jing-pian Peng,* (2003) Effect of IFN g on caspase-3, Bcl-2 and Bax expression, and apoptosis in rabbit placenta, Cytokine. 24(5):201-209.

4. Ruo-lan Xiang, Fei Zhou, Ying Yang and Jing-Pian Peng,* (2003) Construction of the Plasmid pCMV4-rZPC` DNA Vaccine and Analysis of its Contraceptive Potential, Biol Reprod. 68 (5): 1518-1524.

5. Mei-Fang Cheng, Jing-Pian Peng, Jeffrey P.Gardner, (2004) Functional restoration of acoustic units and adult-generated neurons after hypothalamic lesion. Journal of Neurobiology. 60(2):197-213.

6. Shu-Qun Shi, Jing-Pian Peng*, Li Xu, (2005)The beta subunit of mouse chorionic gonadotropin (muCG b ) produced by tumor cells elicits the switch of T-cell immunity response from TH2 to TH1 in mice immunized with genetic vaccine based on rhesus monkey homologous CG b, J GENE MED.7:87 – 96.

7. Shu-Qun Shi, Wang Jin-ling, Jing-Pian Peng,* Jian-Jun Chang, (2005) Oral feeding and Nasal Instillation Immunization with Microtus branditi Lactate Dehydrogenase C Epitope DNA Vaccine Reduce Fertility in Mice via the Specific Antibodies Responses Fertility and Sterility84:781-784

8. Quan-Hong Sun, Jing-Pian Peng*, Hong-Fei Xia, (2005)Effect on expression of RT1-A and RT1-DM molecules treatment with interferon gamma at the maternal-fetal interface of pregnant rat. Human Reproduction , 20(9):2639-2647.

9. Jian-Jun Chang, Jing-Pian Peng*, Ying Yang , Wang Jin-ling, (2006) Study on the Anti-fertility Effects of the Plasmid DNA Vaccine Expressing Partial brLDH-C4. Reprod. 131: 183–192.

10. Li Xu, Jing-Pian Peng*, Shu-Qun Shi, (2006) brZPC partial cDNA reduce fertility via immue responses in mouse. DNA and Cell Biology. 25( 2): 87–94.

11. Quan-Hong Sun, Jing-Pian Peng* and Hong-Fei Xia (2006) IFNg pretreatment sensitizes human choriocarcinoma cells to etoposide-induced apoptosis. Mol. Hum. Reprod. 12(2):99-105.

12. Shu-Qun Shi, Jing-PianPeng,*Yin-Chuan Li, Chuan Qin, Guo-Dong Liang, Li Xu, YingYang, Jin-LingWang, Quan-Hong Sun, (2006) The expression of membrane protein augments the specific responses induced by SARS-CoV nucleocapsid DNA immunization. Mol Immunol. 43(11):1791-1798.

13. Hong-Fei Xia, Jing-Pian Peng *, Quan-Hong Sun , Ying Yang , and Mei-Ling Liu, (2006) Effects of IL-1 beta on RT1-A/RT1-DM at the maternal-fetal interface during pregnancy in rats. Frontiers in Bioscience. 11, 2868-2875.

14. Gang Zhao, Shu-Qun Shi, Ying Yang, and Jing-Pian Peng,* (2006) M and N proteins of SARS coronavirus induce apoptosis in HPF cells. Cell Biol Toxicol 22: 313–322.

15. Shu-Qun Shi, Li Xu, Gang Zhao, Yang Ying, Jing-Pian Peng*,(2006) Apoptosis and tumor inhibition induced by human chorionic gonadotropin beta in mouse breast carcinoma. Journal of Molecular Medicine.-jmm. 84:933–941.

16. Li Xu, Shu-Qun Shi, Ying Yang, Jing-Pian Peng*, (2007) Researches on four cDNA fragments from rabbit ZP3: their immunogenicity and effects on fertility, Fertility and Sterility. 87(2):381-390.

17.Hong-Fei Xia, Quan-Hong Sun and Jing-Pian Peng,* (2007) Effect of interferon-g treatment on the expression of interleukin-1b at the maternal–fetal interface of pregnant rats. Reproduction, Fertility and Development. 19, 510–519.

18. Quan-Hong Sun ?Jing-Pian Peng* Hong-Fei Xia Ying Yang, (2007) Interferon gamma promote apoptosis of uterus and placenta in pregnant rat and human cytotrophoblast cells. Journal of Interferon & Cytokine Research. 27: 567-578.

19. Hong-Fei Xia,? Jing Sun, Quan-Hong Sun, Ying Yang, Jing-Pian Peng*(2008) Implantation associated gene-1 (Iag-1): a novel gene involved in the early process of embryonic implantation in rat. Human Reproduction. 23(7): 1581-1593.

20. Jing Sun, Hong-Fei Xia, YingYang, Jing-Pian Peng,*(2008) The antifertility effects of DNA vaccine-induced immune responses against uroguanylin. Vaccine. online on june, 2008)

 
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  Address: The State Key Laboratory of Reproductive Biology
Institute of Zoology Chinese Academy of Sciences
1 Beichen West Road, Chaoyang District, Beijing 100101, P.R.China
Telephone: 86-10-64807050
Fax: 86-10-64807316　　
Email: wangjq@ioz.ac.cn, or sunqy@ioz.ac.cn